The all new pco.edge 10 bi CLHS is PCO's next level sCMOS camera with unprecedented imaging performance. The sensor incorporates microlenses and a full pixel height deep trench isolation for crosstalk suppression resulting in an excellent MTF. An extremely low dark current and a readout noise of 0.8 electrons is achieved by thermal stabilization and active cooling. This new camera is a perfect choice for applications in microscopy, life science, and physical science.