PIXIS-XO x-ray cameras utilizes back-illuminated (BI) CCDs without AR coating, for direct detection of the widest range of X-rays between ~ 10 eV and 30 keV. With a 2048 x 2048 imaging array, 13.5 µm pixels, 100% fill factor, low noise electronics and -50° C to -70° C thermoelectric cooling with either air or water, this system is ideal for worry-free operation in research and OEM environments. The rotatable conflat flange with high-vacuum-seal design, software selectable gains and readout speeds make these cameras well suited for ultra-high vacuum applications.